Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor used in the therapy of multiple myeloma. Its synthesis or analyze is critical for making certain the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets particular kinds of most cancers, which includes Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation system and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the treatment method of breast most cancers. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis Abiraterone of paclitaxel, a chemotherapy drug productive in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the cure of colorectal most cancers and modest mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have numerous applications, which include antiviral Qualities.
Vildagliptin Bortezomib intermediate Intermediates: Used in the manufacture of vildagliptin, an oral drug for kind two diabetes that inhibits the enzyme DPP-four to regulate blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is associated with the synthesis of assorted gluconic acid derivatives, that happen to be used in food items, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication made use of to handle style 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).